Description

(Bromomethyl)Triethylsilane CAS NO 1112-53-4 is a versatile organosilicon reagent featuring a reactive bromomethyl group. This compound is a critical building block in organic synthesis, valued for its ability to introduce the triethylsilyl-protected hydroxymethyl group into target molecules. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key reagent in the synthesis of active pharmaceutical ingredients (APIs), particularly for introducing protected functional groups.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides as a versatile alkylating and silylating agent.
• Polymer & Material Science: Serves as a monomer or functionalization agent in the development of specialty silicones and silicon-containing polymers.
• Organic Synthesis Building Block: Employed in homologation reactions, chain extensions, and the preparation of silyl enol ethers and other organometallic precursors.
• Cross-Coupling Reactions: Acts as an electrophile in various palladium-catalyzed cross-coupling processes to form carbon-carbon bonds.
• Protecting Group Chemistry: The triethylsilyl (TES) group is used to protect alcohols, with the bromomethyl handle allowing for further transformation.

Basic Information

Product Name	(Bromomethyl)Triethylsilane
CAS No.	1112-53-4
Molecular Formula	C7H17BrSi
Molecular Weight	209.20 g/mol
Synonyms	Triethyl(bromomethyl)silane; Bromomethyltriethylsilane; (Bromomethyl)triethylsilicon; Triethylsilylmethyl bromide; Silane, bromomethyltriethyl-; (Bromomethyl)triethylsilane; Bromo(methyl)triethylsilane; EINECS 214-192-8
EINECS	214-192-8

Quality Control

Our (Bromomethyl)Triethylsilane is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for demanding synthetic applications. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, identity, and impurity profiles. Our quality management system adheres to cGMP principles where applicable, supporting its use in regulated research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Due to its highly volatile nature, keep containers tightly sealed when not in use and away from heat and ignition sources. Handle and store under an inert atmosphere (e.g., nitrogen or argon) for optimal long-term stability, as it may be sensitive to strong bases and moisture.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 97.0%
Density (at 20°C)	1.10 - 1.15 g/mL
Refractive Index (n20D)	1.450 - 1.455
Related Substances (GC)	Total impurities ≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.