Description

1,1-Cyclobutanediacetic Acid is a versatile dicarboxylic acid derivative featuring a cyclobutane ring, which serves as a valuable synthetic building block in advanced organic chemistry. Its unique fused ring structure provides a rigid scaffold that is crucial for constructing complex molecular architectures with specific spatial configurations. This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for applications in medicinal chemistry and material science.

Application

• Pharmaceutical Intermediate: A key starting material or intermediate in the synthesis of novel active pharmaceutical ingredients (APIs), particularly those requiring constrained, bicyclic frameworks.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and plant growth regulators where its structure can impart specific biological activity.
• Polymer Chemistry: Serves as a monomer or cross-linking agent for producing specialty polyesters, polyamides, and other polymers with enhanced thermal or mechanical properties.
• Ligand and Catalyst Development: Employed in the preparation of chiral ligands and organocatalysts for asymmetric synthesis.
• Material Science Research: Investigated for creating novel organic frameworks, crystal engineering, and advanced functional materials.
• Chemical Biology Probes: Utilized as a core structure in designing molecular probes and inhibitors for studying enzyme function and biological pathways.

Basic Information

Product Name	1,1-Cyclobutanediacetic Acid
CAS No.	1075-98-5
Molecular Formula	C8H12O4
Molecular Weight	172.18 g/mol
Synonyms	Cyclobutane-1,1-diacetic Acid; 1,1-Bis(carboxymethyl)cyclobutane; Cyclobutanedicarboxylic Acid, 1,1-Dimethyl-; NSC 163022; 1,1-Cyclobutanediyldiacetic Acid
EINECS	214-067-4

Quality Control

Our 1,1-Cyclobutanediacetic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and FTIR, to ensure identity, purity, and consistency. We provide detailed Certificates of Analysis (COA) with every shipment, documenting all critical parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring traceability and reliability for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents, strong bases, and heat sources. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.