Description

2-Bromofluorobenzene is a versatile halogenated aromatic building block essential for advanced organic synthesis. Its unique combination of bromine and fluorine substituents makes it a critical intermediate for constructing complex molecules in high-value industries. This compound is primarily sought after by pharmaceutical, agrochemical, and specialty chemical manufacturers for applications in cross-coupling reactions, material science, and as a precursor for liquid crystals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs) via Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and pesticides, leveraging the fluorine atom for enhanced biological activity and metabolic stability.
• Liquid Crystal & OLED Materials: Serves as a building block for fluorine-containing liquid crystals and organic light-emitting diode (OLED) materials, where fluorine substitution fine-tunes electronic properties.
• Specialty Polymer Monomer: Employed in the production of high-performance polymers and resins with specific thermal and chemical resistance profiles.
• Organic Synthesis Reagent: A valuable reagent for introducing the 2-bromofluorophenyl moiety into more complex molecular architectures in research and development.
• Fluorine Chemistry Research: Used in academic and industrial R&D to study structure-activity relationships and develop new fluorination methodologies.

Basic Information

Product Name	2-Bromofluorobenzene
CAS No.	1072-85-1
Molecular Formula	C6H4BrF
Molecular Weight	175.00 g/mol
Synonyms	1-Bromo-2-fluorobenzene; o-Bromofluorobenzene; 2-Fluorobromobenzene; o-Fluorobromobenzene; Fluorobenzene, 2-bromo-; Benzene, 1-bromo-2-fluoro-; (2-Bromophenyl) fluoride
EINECS	214-007-1

Quality Control

Our 2-Bromofluorobenzene is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including GC, HPLC, and NMR, to ensure high purity and consistency. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong acids and organic solvents. Recommended storage temperature is between 15°C and 25°C. Keep container tightly sealed when not in use to prevent moisture absorption and volatilization.

Specification

Item	Specification
Appearance	Clear, colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.1%
Density (at 20°C)	1.590 - 1.610 g/mL
Refractive Index (n20D)	1.525 - 1.535

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.