Description

4-Bromo-2-Chloro-6-Fluorophenol is a halogenated phenol derivative that serves as a versatile and critical building block in advanced organic synthesis. Its unique substitution pattern makes it a valuable intermediate for constructing complex molecules with specific electronic and steric properties. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and material science sectors for developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring a halogenated phenolic core.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and pesticides, where the halogen atoms contribute to biological activity.
• Liquid Crystal & OLED Materials: Serves as a building block for creating advanced organic electronic materials due to its ability to modify molecular polarity and conjugation.
• Polymer Modification: Acts as a monomer or functionalizing agent to introduce halogenated phenolic groups into polymer chains, enhancing flame retardancy or other properties.
• Organic Synthesis Reagent: Employed in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and nucleophilic aromatic substitution to create complex biaryl and heterocyclic structures.
• Dye & Pigment Intermediate: Used in the production of specialized dyes and pigments where halogen atoms improve lightfastness and color properties.

Basic Information

Item	Detail
Product Name	4-Bromo-2-Chloro-6-Fluorophenol
CAS No.	1045-79-0
Molecular Formula	C6H3BrClFO
Molecular Weight	225.44 g/mol
Synonyms	2-Chloro-4-bromo-6-fluorophenol; 6-Fluoro-2-chloro-4-bromophenol; 4-Bromo-2-chloro-6-fluoro-1-hydroxybenzene; Phenol, 4-bromo-2-chloro-6-fluoro-; 1-Hydroxy-4-bromo-2-chloro-6-fluorobenzene; 2-Chloro-6-fluoro-4-bromophenol; 4-Br-2-Cl-6-F-Phenol
EINECS	Contact for details

Quality Control

Our 4-Bromo-2-Chloro-6-Fluorophenol is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. We provide comprehensive Certificates of Analysis (COA) for each lot, detailing purity, identity, and impurity profiles. Our quality management system is designed to meet the stringent requirements of cGMP and ISO standards for advanced chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong bases, oxidizing agents, and sources of ignition. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	68 - 72 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.