Description

4-Tetrahydrothiophen-3-Yl-Morpholine is a versatile heterocyclic building block containing both morpholine and tetrahydrothiophene moieties. This compound is valued for its unique structure, which makes it a critical intermediate in the synthesis of complex molecules, particularly in pharmaceutical research and development. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon in the research and production of new drug candidates, particularly those targeting the central nervous system or requiring specific heterocyclic frameworks.
• Agrochemical Synthesis: Used in the development of advanced pesticides, herbicides, and fungicides where the morpholine and sulfur-containing rings impart specific biological activity.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of novel polymers, dyes, and organic electronic materials due to its electron-donating properties and rigid structure.
• Chemical Biology Probes: Useful for designing molecular probes and inhibitors to study enzyme function and biological pathways.
• Custom Synthesis and Scale-Up: Supplied for contract research organizations (CROs) and CDMOs requiring high-purity building blocks for client projects.

Basic Information

Product Name	4-Tetrahydrothiophen-3-Yl-Morpholine
CAS No.	1006-74-2
Molecular Formula	C8H15NOS
Molecular Weight	173.28 g/mol
Synonyms	3-Morpholin-4-ylthiolane; 4-(Tetrahydrothiophen-3-yl)morpholine; 3-Morpholinothiolane; 3-(4-Morpholinyl)tetrahydrothiophene; Tetrahydro-3-morpholinothiophene; 3-Morpholino-1-thiacyclopentane; 1006-74-2; 4-(Thiolan-3-yl)morpholine
EINECS	Contact for details

Quality Control

Our 4-Tetrahydrothiophen-3-Yl-Morpholine is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and Karl Fischer titration, to ensure identity, purity, and consistency. We provide detailed Certificates of Analysis (COA) with each shipment, confirming compliance with agreed specifications. Our quality commitment supports applications requiring high-purity intermediates under cGMP or ISO 9001 guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Residual Solvents (GC)	Complies with ICH Q3C

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.