Description

2-Amino-4-Chlorothiophenol is a versatile aromatic thiol derivative that serves as a critical building block in advanced organic synthesis. Its bifunctional nature, featuring both an amino and a thiol group on a chlorinated benzene ring, makes it an indispensable intermediate for constructing complex heterocyclic and pharmaceutical compounds. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of benzothiazole and thiazolopyridine derivatives, which are core structures in various drug candidates.
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and pesticides that require a chlorinated aniline-thiol motif for biological activity.
• Dye and Pigment Manufacturing: Acts as a coupling agent and intermediate for producing sulfur-containing azo dyes and organic pigments.
• Polymer Modification: Serves as a chain transfer agent or functional monomer to introduce thiol groups into polymers for cross-linking or surface modification.
• Chemical Research: Valuable reagent in academic and industrial R&D for exploring new synthetic pathways to sulfur-nitrogen heterocycles.
• Corrosion Inhibitor Formulation: Utilized as a component in specialty formulations designed to protect metals, leveraging its ability to form stable complexes on surfaces.

Basic Information

Product Name	2-Amino-4-Chlorothiophenol
CAS No.	1004-00-8
Molecular Formula	C6H6ClNS
Molecular Weight	159.63 g/mol
Synonyms	4-Chloro-2-aminobenzenethiol; 2-Amino-4-chlorobenzenethiol; 4-Chloro-o-aminothiophenol; 1-Amino-3-chloro-4-mercaptobenzene; Benzenethiol, 2-amino-4-chloro-; (2-Amino-4-chlorophenyl)thiol; 4-Chloro-2-mercaptoaniline
EINECS	213-710-4

Quality Control

Our 2-Amino-4-Chlorothiophenol is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, impurity profile, and physical characteristics. Our quality commitment aligns with cGMP principles where applicable, and we support our clients' regulatory needs for pharmaceutical and agrochemical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to light yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	68°C - 72°C
Loss on Drying	≤ 1.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.