Description

Choline Hydroxide is a versatile organic strong base, commonly supplied as a concentrated aqueous solution. It serves as a critical reagent and intermediate in the synthesis of high-value fine chemicals and pharmaceuticals, offering a less corrosive and more selective alternative to inorganic alkalis. This compound is essential for manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors, particularly for processes requiring a strong, non-nucleophilic base under mild conditions.

Application

• Pharmaceutical Synthesis: Key intermediate and catalyst in the production of active pharmaceutical ingredients (APIs), including cholinergic agents and other nitrogen-containing compounds.
• Agrochemical Manufacturing: Used in the synthesis of quaternary ammonium-based herbicides, fungicides, and plant growth regulators.
• Chemical Intermediate: Serves as a precursor for the production of choline salts (e.g., choline chloride, choline bitartrate) and other specialty surfactants.
• Catalyst & Reagent: Employed as a strong base in organic synthesis, deprotonation reactions, and hydrolysis processes where mineral bases are unsuitable.
• Electronics Industry: Utilized in photoresist developers and as an etchant in the manufacturing of printed circuit boards (PCBs) and semiconductors.
• Research & Development: A valuable reagent in academic and industrial R&D labs for methodological development and scale-up studies.

Basic Information

Product Name	Choline Hydroxide
CAS No.	123-41-1
Molecular Formula	C5H15NO2
Molecular Weight	121.18 g/mol
Synonyms	2-Hydroxyethyltrimethylammonium hydroxide; (2-Hydroxyethyl)trimethylammonium hydroxide; Choline, hydroxide; Biocolina; Hepacholine; Lipotril; Luridine; Vitamin J; (β-Hydroxyethyl)trimethylammonium hydroxide
EINECS	204-625-1

Quality Control

Our Choline Hydroxide is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing to ensure it meets the required specifications for purity, concentration, and impurity profiles. We provide full traceability and support our products with detailed Certificates of Analysis (COA), which are available upon request. Our quality commitment aligns with cGMP principles where applicable, ensuring reliability for critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, containers must be kept tightly sealed to prevent absorption of atmospheric moisture and carbon dioxide, which can degrade product quality.

Specification

Item	Specification
Appearance	Colorless to pale yellow aqueous solution
Identification (IR)	Conforms
Assay (Choline Hydroxide)	40 - 50 % w/w (or as specified)
pH	> 13
Heavy Metals (as Pb)	< 10 ppm
Residual Solvents	Meets ICH guidelines
Chloride (Cl)	< 0.1 %

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.