Description

2-Amino-1-(4-Nitrophenyl)-1,3-Propanediol is a versatile organic intermediate characterized by its amino and diol functional groups attached to a nitrophenyl backbone. This compound matters for its role as a key chiral building block in the synthesis of complex molecules, offering a critical point of stereochemical control. It is primarily needed by pharmaceutical R&D and fine chemical manufacturers for developing active pharmaceutical ingredients (APIs), chiral catalysts, and advanced materials.

Application

• Pharmaceutical Intermediate: A crucial chiral precursor in the synthesis of various active pharmaceutical ingredients (APIs), particularly for cardiovascular and central nervous system drugs.
• Asymmetric Catalyst Synthesis: Used to construct chiral ligands and organocatalysts for enantioselective synthesis in fine chemical production.
• Agrochemical Research: Serves as a building block for developing novel, high-efficacy pesticides and herbicides with specific stereochemistry.
• Dye and Pigment Intermediate: Utilized in the synthesis of specialized azo dyes and nitro-aromatic based colorants.
• Polymer Modification: Acts as a monomer or cross-linking agent for creating specialty polymers with enhanced thermal or mechanical properties.
• Biochemical Research: Employed in academic and industrial research for studying enzyme inhibition and receptor binding activities.

Basic Information

Product Name	2-Amino-1-(4-Nitrophenyl)-1,3-Propanediol
CAS No.	119-62-0
Molecular Formula	C9H12N2O4
Molecular Weight	212.20 g/mol
Synonyms	1,3-Propanediol, 2-amino-1-(4-nitrophenyl)-; 4-Nitro-α-(aminomethyl)benzyl alcohol; 2-Amino-1-(p-nitrophenyl)-1,3-propanediol; (R,S)-2-Amino-1-(4-nitrophenyl)-1,3-propanediol; (±)-2-Amino-1-(4-nitrophenyl)-1,3-propanediol; p-Nitro-α-(aminomethyl)benzyl alcohol; AMPD; 4-Nitroamphetamine diol
EINECS	204-340-5

Quality Control

Our 2-Amino-1-(4-Nitrophenyl)-1,3-Propanediol is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral purity assessment, to ensure it meets the high standards required for pharmaceutical and fine chemical applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, residual solvents, and specific tests is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents and strong acids. The compound may be hygroscopic; keep the container tightly sealed to minimize moisture absorption.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.