Description

2-[2-(3-Aminopropoxy)Ethoxy]Ethanol is a versatile amino-functionalized polyether glycol with a terminal primary amine group. This bifunctional structure, containing both hydrophilic ether linkages and a reactive amine, makes it a valuable intermediate for creating tailored polymers and surface-active agents. It is particularly sought after by formulators and researchers in the pharmaceutical, polymer, and specialty chemical industries. Its ability to act as a spacer or linker molecule enables the synthesis of functional materials with specific properties.

Application

• Pharmaceutical Intermediate: Used in the synthesis of drug conjugates, prodrugs, and as a hydrophilic linker in antibody-drug conjugates (ADCs).
• Polymer Modification: Serves as a chain extender or crosslinking agent in polyurethane and epoxy resin formulations, imparting flexibility and amine functionality.
• Surface Active Agent: Acts as a precursor for cationic surfactants and emulsifiers used in personal care and industrial cleaning products.
• Bioconjugation Chemistry: Utilized to attach biomolecules (e.g., proteins, peptides) to surfaces, particles, or other molecules via its reactive amine terminus.
• Chelating Agent Synthesis: A building block for creating multifunctional chelators used in medical imaging and water treatment.
• Coating Additive: Incorporated into coatings to improve adhesion, dispersion, and moisture resistance.

Basic Information

Product Name	2-[2-(3-Aminopropoxy)Ethoxy]Ethanol
CAS No.	112-33-4
Molecular Formula	C7H17NO3
Molecular Weight	163.22 g/mol
Synonyms	3-[2-(2-Hydroxyethoxy)ethoxy]propylamine; 2,2'-(3-Aminopropoxy)diethanol; Amino-PEG3-alcohol; 3,6-Dioxa-1,9-nonanediol, 9-amino-; APE; Jeffamine® XTJ-509 (typical trade name); O-(2-Aminoethyl)-O'-(2-hydroxyethyl)diethylene glycol; 3-(2-(2-Hydroxyethoxy)ethoxy)propan-1-amine
EINECS	203-961-1

Quality Control

Our 2-[2-(3-Aminopropoxy)Ethoxy]Ethanol is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing to ensure high purity and consistency, meeting the requirements for advanced synthetic applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive). Keep container tightly sealed under a dry inert atmosphere (e.g., nitrogen) to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC or Titration)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Color (APHA)	≤ 50

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.