Description

Ru 58841 is a potent and selective non-steroidal antiandrogen compound, widely recognized for its research applications in dermatology and hair biology. Its primary value lies in its ability to locally inhibit the androgen receptor, offering a targeted approach for scientific investigation without significant systemic effects. This makes it a critical research chemical for pharmaceutical R&D teams, cosmetic science laboratories, and academic institutions focused on developing novel treatments for androgen-dependent conditions.

Application

• Hair Loss Research: A key compound in preclinical studies for androgenetic alopecia (male and female pattern hair loss) to investigate local antiandrogenic mechanisms.
• Dermatological R&D: Used in the development and testing of topical formulations aimed at treating acne vulgaris and other androgen-mediated skin disorders.
• Biochemical Assays: Serves as a reference standard and active agent in in vitro assays to study androgen receptor binding affinity and signal transduction pathways.
• Cosmetic Science: Employed in the research of advanced cosmetic actives targeting sebum regulation and hair follicle miniaturization.
• Pharmacology Studies: Utilized in animal models to assess the efficacy and local tolerability of novel antiandrogen therapies.

Basic Information

Product Name	Ru 58841
CAS No.	154992-24-2
Molecular Formula	C19H14F6N2O2
Molecular Weight	416.32 g/mol
Synonyms	RU-58841; RU58841; 2,2,2-Trifluoro-N-[4-cyano-3-(trifluoromethyl)phenyl]-N'-(4-nitrophenyl)urea; PSK-3841; 4-Cyano-3-(trifluoromethyl)phenyl 2,2,2-trifluoro-1-(4-nitrophenylamino)-1-oxoethan-2-ylcarbamate; Non-steroidal antiandrogen RU-58841
EINECS	Contact for details

Quality Control

Our Ru 58841 is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity for research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant standards for research chemicals, and specifications can be aligned with client requirements for advanced R&D projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/IR)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.