Description

2-Azetidinone,4-(Acetyloxy)-3-(1-Methylethyl)-,(3S-Cis)-(9Ci) is a high-purity, chiral β-lactam derivative, a crucial advanced pharmaceutical intermediate (API) for the synthesis of novel therapeutic agents. Its precise stereochemistry and functional groups make it an indispensable building block for medicinal chemists developing targeted, high-efficacy drugs. This compound is primarily utilized in research and development for the pharmaceutical and biotechnology sectors, particularly in the creation of new antibiotics and enzyme inhibitors.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and production of novel β-lactam antibiotics and other active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Serves as a critical scaffold for structure-activity relationship (SAR) studies and the development of new drug candidates targeting bacterial enzymes.
• Organic Synthesis: Used as a versatile building block in complex organic synthesis, particularly for introducing the azetidinone (β-lactam) ring system with defined stereochemistry.
• Biochemical Research: Employed in the study of enzyme mechanisms and inhibition, especially for serine proteases and penicillin-binding proteins.
• Process Development: Utilized in the scale-up and optimization of synthetic routes for pharmaceutical manufacturing under current Good Manufacturing Practice (cGMP) standards.

Basic Information

Product Name	2-Azetidinone,4-(Acetyloxy)-3-(1-Methylethyl)-,(3S-Cis)-(9Ci)
CAS No.	127127-63-3
Molecular Formula	C8H13NO3
Molecular Weight	171.19 g/mol
Synonyms	(3S,4S)-4-Acetoxy-3-isopropylazetidin-2-one; 4-Acetoxy-3-isopropyl-2-azetidinone; 3-Isopropyl-4-acetoxy-2-azetidinone; (3S-cis)-4-(Acetyloxy)-3-(1-methylethyl)-2-azetidinone; β-Lactam derivative; Chiral azetidinone; Advanced pharmaceutical intermediate (API)
EINECS	Contact for details

Quality Control

Our 2-Azetidinone,4-(Acetyloxy)-3-(1-Methylethyl)-,(3S-Cis)-(9Ci) is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and pharmaceutical applications. We provide comprehensive Certificates of Analysis (COA) for each lot, detailing purity, chiral purity, and impurity profiles. Our quality systems are designed to support development work that may scale under cGMP guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This product is light-sensitive and should be handled and stored away from direct light exposure to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.