Description

3-Pyrrolidinecarboxamide, 1-(2-Chloro-3-Hydroxyphenyl)- is a high-purity, synthetically derived pyrrolidine derivative of significant interest in advanced organic synthesis. This compound serves as a critical chiral building block and intermediate for the development of novel active pharmaceutical ingredients (APIs) and fine chemicals. It is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for its utility in constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new therapeutic agents, particularly for central nervous system (CNS) and metabolic disorder targets.
• Agrochemical Synthesis: Used in the production of advanced crop protection agents and herbicides, leveraging its unique heterocyclic structure.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Chemical Research & Development: Employed in academic and industrial R&D for exploring new reaction pathways and synthesizing novel chemical entities.
• Fine Chemical Production: Integral to the multi-step synthesis of complex, high-value specialty chemicals and flavors/fragrances.

Basic Information

Product Name	3-Pyrrolidinecarboxamide, 1-(2-Chloro-3-Hydroxyphenyl)-
CAS No.	925233-25-6
Molecular Formula	C11H13ClN2O2
Molecular Weight	240.69 g/mol
Synonyms	1-(2-Chloro-3-hydroxyphenyl)pyrrolidine-3-carboxamide; 1-(2-Chloro-3-hydroxyphenyl)-3-pyrrolidinecarboxamide; 1-(2-Chloro-3-hydroxyphenyl)pyrrolidine-3-carboxylic acid amide; 3-Carbamoylpyrrolidine, 1-(2-chloro-3-hydroxyphenyl)-; Pyrrolidine-3-carboxamide, 1-(2-chloro-3-hydroxyphenyl)-; 925233-25-6; 1-(2-Chloro-3-hydroxy-phenyl)-pyrrolidine-3-carboxylic acid amide
EINECS	Contact for details

Quality Control

Our 3-Pyrrolidinecarboxamide, 1-(2-Chloro-3-Hydroxyphenyl)- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your most demanding synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The product is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if necessary to prevent degradation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Purity (HPLC, Area %)	≥99.0%
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.