Description

4'-Bromo-2,2-dimethylpropiophenone is a high-purity brominated aromatic ketone, serving as a critical advanced intermediate in organic synthesis. Its value lies in providing a sterically hindered, reactive bromo-substituted phenyl framework essential for constructing complex molecular architectures. This compound is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for developing active ingredients and novel materials.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring a bromo-substituted, hindered aromatic moiety.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and plant growth regulators.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in transition metal catalysis and asymmetric synthesis.
• Material Science Research: Employed in the development of organic electronic materials, liquid crystals, and polymers with specific optical or electronic properties.
• Chemical Research: A versatile reagent for Friedel-Crafts acylation reactions and further functionalization to create diverse chemical libraries.

Basic Information

Product Name	4'-Bromo-2,2-dimethylpropiophenone
CAS No.	30314-45-5
Molecular Formula	C11H13BrO
Molecular Weight	241.12 g/mol
Synonyms	1-(4-Bromophenyl)-2,2-dimethylpropan-1-one; p-Bromo-2,2-dimethylpropiophenone; 4-Bromophenyl tert-butyl ketone; 2,2-Dimethyl-1-(4-bromophenyl)-1-propanone; 4'-Bromo-α,α-dimethylpropiophenone; 1-(4-Bromophenyl)-2,2-dimethyl-1-propanone; tert-Butyl 4-bromophenyl ketone
EINECS	Contact for details

Quality Control

Our 4'-Bromo-2,2-dimethylpropiophenone is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are provided with every shipment to guarantee traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents and bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.