Description

8-Bromo-6-(Trifluoromethoxy)-1,2,3,4-Tetrahydroquinoline-2-One 95+% is a high-purity, advanced pharmaceutical intermediate characterized by its brominated and trifluoromethoxy-substituted tetrahydroquinolinone scaffold. This compound matters as a critical building block for medicinal chemistry research and development, enabling the synthesis of novel bioactive molecules with potential applications in drug discovery. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the synthesis of potential drug candidates, particularly for central nervous system (CNS) and oncology targets.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization programs due to its unique halogenated and fluorinated motifs.
• Agrochemical Development: Acts as a precursor for novel active ingredients in crop protection products, leveraging its heterocyclic structure.
• Chemical Biology Probes: Utilized in the development of molecular probes for studying enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: A starting material for the custom production of complex, high-value specialty chemicals for clients.
• Academic Research: Employed in university and institutional labs for methodological development in organic synthesis and heterocyclic chemistry.

Basic Information

Product Name	8-Bromo-6-(Trifluoromethoxy)-1,2,3,4-Tetrahydroquinoline-2-One 95+%
CAS No.	2149597-02-2
Molecular Formula	C10H7BrF3NO2
Molecular Weight	310.07 g/mol
Synonyms	8-Bromo-6-(trifluoromethoxy)-3,4-dihydro-1H-quinolin-2-one; 8-Bromo-6-(trifluoromethoxy)-1,2,3,4-tetrahydroquinolin-2-one; 2(1H)-Quinolinone, 8-bromo-6-(trifluoromethoxy)-1,2,3,4-tetrahydro-; 2149597-02-2; 8-Bromo-6-trifluoromethoxy-1,2,3,4-tetrahydroquinolin-2-one
EINECS	Contact for details

Quality Control

Our 8-Bromo-6-(Trifluoromethoxy)-1,2,3,4-Tetrahydroquinoline-2-One 95+% is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency meet the specified standards. Certificates of Analysis (COA) documenting all critical quality attributes are available upon request to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases and strong oxidizing agents. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.