Description

5-Bromo-6-Chloronicotinic Acid is a high-purity halogenated nicotinic acid derivative, serving as a critical pharmaceutical intermediate and versatile building block in organic synthesis. Its value lies in its unique substitution pattern, which enables the precise construction of complex heterocyclic molecules essential for modern drug discovery. This compound is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, leveraging its halogenated pyridine core.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in transition metal catalysis and coordination chemistry.
• Material Science Research: Employed in the synthesis of functionalized organic materials and molecular components for electronic applications.
• Custom Synthesis and Contract Manufacturing: A fundamental starting material for custom synthesis projects and scale-up processes in fine chemical production.
• Academic and R&D Laboratories: Utilized in medicinal chemistry programs for structure-activity relationship (SAR) studies and novel compound library generation.

Basic Information

Product Name	5-Bromo-6-Chloronicotinic Acid
CAS No.	29241-62-1
Molecular Formula	C6H3BrClNO2
Molecular Weight	236.45 g/mol
Synonyms	6-Chloro-5-bromonicotinic acid; 5-Bromo-6-chloropyridine-3-carboxylic acid; 3-Pyridinecarboxylic acid, 5-bromo-6-chloro-; 5-Bromo-6-chloro-3-pyridinecarboxylic acid; 5-Bromo-6-chloronicotinic acid; 29241-62-1; Nicotinic acid, 5-bromo-6-chloro-
EINECS	Contact for details

Quality Control

Our 5-Bromo-6-Chloronicotinic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our commitment to quality supports compliance with cGMP and ISO standards for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong bases and reducing agents. For long-term storage, consider conditions under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.