Description

1,3-Dioxolo4,5-Cpyridin-7-Ol, 4-(1,1-Dimethylethyl)Dimethylsilyloxymethylhexahydro-2,2-Dimethyl-, 3As-(3A.Alpha.,4.Beta.,7.Alpha.,7A.Alpha.)- is a complex, high-purity organosilicon-protected intermediate with a fused dioxolopyridine structure. This compound matters for its role as a critical building block in the synthesis of advanced pharmaceutical agents and fine chemicals, offering precise stereochemical control. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing sophisticated molecular architectures.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the multi-step synthesis of complex active pharmaceutical ingredients (APIs), particularly those targeting neurological or metabolic disorders.
• Agrochemical Research: Used in the development of novel pesticides and herbicides, where its unique heterocyclic structure can contribute to biological activity.
• Ligand & Catalyst Precursor: Acts as a starting material for synthesizing specialized ligands used in asymmetric catalysis and transition metal complexes.
• Fine Chemical Synthesis: Employed in academic and industrial research laboratories for the construction of complex natural product analogs and novel organic molecules.
• Process Chemistry Development: Utilized in scaling up synthetic routes from laboratory to pilot plant scale, where its defined stereochemistry is crucial for reproducibility.

Basic Information

Item	Detail
Product Name	1,3-Dioxolo4,5-Cpyridin-7-Ol, 4-(1,1-Dimethylethyl)Dimethylsilyloxymethylhexahydro-2,2-Dimethyl-, 3As-(3A.Alpha.,4.Beta.,7.Alpha.,7A.Alpha.)-
CAS No.	151252-21-0
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	4-(tert-Butyldimethylsilyloxymethyl)hexahydro-2,2-dimethyl-1,3-dioxolo[4,5-c]pyridin-7-ol; tert-Butyldimethylsilyl ether derivative of a hexahydro-1,3-dioxolo[4,5-c]pyridin-7-ol; TBS-protected dioxolopyridinol intermediate; (3aα,4β,7α,7aα)-4-[[(1,1-Dimethylethyl)dimethylsilyl]oxymethyl]hexahydro-2,2-dimethyl-1,3-dioxolo[4,5-c]pyridin-7-ol; CAS 151252-21-0
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Every batch is characterized using advanced analytical techniques including HPLC, GC, NMR, and mass spectrometry to confirm identity, purity, and stereochemical integrity. Certificates of Analysis (COA) detailing all relevant specifications are available upon request. We adhere to cGMP principles where applicable to support our clients' regulatory filings.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases and fluorides. For long-term storage under inert atmosphere, please contact our technical team for specific recommendations.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.