Description

2-Chloro-1H-Imidazo[4,5-B]Pyridine Hydrochloride is a high-purity, heterocyclic organic compound that serves as a critical building block in advanced chemical synthesis. Its value lies in its role as a versatile intermediate for constructing complex molecular architectures, particularly in the development of active pharmaceutical ingredients (APIs). This compound is essential for research and production teams in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop new therapeutic agents and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, oncology, and anti-infective therapies.
• Agrochemical Research: Used in the development of new generation herbicides, fungicides, and plant growth regulators due to its bioactive heterocyclic core.
• Material Science: Serves as a building block for creating organic semiconductors, ligands for catalysis, and other functional organic materials.
• Chemical Biology & Proteomics: Employed in the design and synthesis of molecular probes and enzyme inhibitors for biochemical research.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) producing specialized compounds for clients.

Basic Information

Product Name	2-Chloro-1H-Imidazo[4,5-B]Pyridine Hydrochloride
CAS No.	132261-24-6
Molecular Formula	C6H5Cl2N3
Molecular Weight	190.03 g/mol
Synonyms	2-Chloro-1H-imidazo[4,5-b]pyridine hydrochloride; 2-Chloro-1H-imidazo[4,5-b]pyridine HCl; 2-Chloroimidazo[4,5-b]pyridine hydrochloride; 1H-Imidazo[4,5-b]pyridine, 2-chloro-, hydrochloride (1:1); 2-Chloro-3-azaindole hydrochloride; 2-Chloro-1H-pyrrolo[2,3-b]pyridine hydrochloride (common misnomer); 2-Chloro-7-azaindole hydrochloride
EINECS	Contact for details

Quality Control

Our 2-Chloro-1H-Imidazo[4,5-B]Pyridine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with agreed specifications. Our quality commitment supports applications requiring high standards, including cGMP intermediates for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.