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1-(5'-o-Sulfamoyl-β-Ribofuranosyl)(1,2,4)Triazole-3-Thiocarboxamide CAS NO 123124-29-8


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CAS No.:123124-29-8

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

1-(5'-o-Sulfamoyl-β-Ribofuranosyl)(1,2,4)Triazole-3-Thiocarboxamide is a sophisticated nucleoside analogue with significant biochemical activity. This compound matters as a key intermediate in the research and development of novel antiviral and pharmaceutical agents, offering a unique structural motif for targeted drug design. It is primarily needed by research institutions and pharmaceutical companies engaged in antiviral drug discovery, enzyme inhibition studies, and the synthesis of modified nucleosides for therapeutic applications.

Application

  • Antiviral Research Intermediate: Serves as a critical building block in the synthesis of experimental nucleoside analogues targeting viral polymerases.
  • Pharmaceutical Development: Used in the discovery and optimization of new drug candidates, particularly for RNA virus infections.
  • Biochemical Tool Compound: Employed in enzymatic studies to investigate mechanisms of action and inhibition pathways.
  • Nucleoside Chemistry: A valuable precursor for the chemical modification of ribose and heterocyclic base structures in academic and industrial research.
  • Proteomics & Molecular Biology: Potential use in creating probes or labeled compounds for studying nucleic acid-protein interactions.

Basic Information

Product Name 1-(5'-o-Sulfamoyl-β-Ribofuranosyl)(1,2,4)Triazole-3-Thiocarboxamide
CAS No. 123124-29-8
Molecular Formula C8H12N6O6S2
Molecular Weight 344.35 g/mol
Synonyms 1-(5'-O-Sulfamoyl-β-D-ribofuranosyl)-1,2,4-triazole-3-thiocarboxamide; 1-(5'-O-Sulfamoyl-β-D-ribofuranosyl)-1H-1,2,4-triazole-3-carbothioamide; 5'-O-Sulfamoyl-3-carbamothioyl-1,2,4-triazol-1-yl β-D-ribofuranose; 3-Carbamothioyl-1-(5-O-sulfamoyl-β-D-ribofuranosyl)-1H-1,2,4-triazole; Ribavirin sulfamate analogue; 1,2,4-Triazole-3-thiocarboxamide ribofuranosyl sulfamate derivative
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Quality Control

Our 1-(5'-o-Sulfamoyl-β-Ribofuranosyl)(1,2,4)Triazole-3-Thiocarboxamide is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity for research applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions when possible to maintain stability.

Specification

Item Specification
Appearance White to off-white powder
Identification (IR) Conforms to structure
Purity (HPLC) ≥ 98.0%
Water Content (KF) ≤ 1.0%
Residue on Ignition ≤ 0.5%
Heavy Metals ≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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